Reconstruction of Nasal Deformity in Wegener's Granulomatosis: Contraindication or Benefit?

作者：Vogt Peter M; Gohritz Andreas; Haubitz Marion; Steiert Andreas^*

来源：Aesthetic Plastic Surgery, 2011, 35(2): 156-161.

DOI：10.1007/s00266-010-9568-9

• Costal cartilage
• Immunosuppression
• Long-term results
• L-strut
• Saddle-nose deformity
• Wegener's granulomatosis

Saddle-nose deformity is a well-recognized stigma of patients affected by Wegener granulomatosis (WG). However, plastic surgical repair is seldom performed. In this study, the authors aimed to evaluate their own patients exclusively reconstructed by costal cartilage L-strut of the nose for this specific deformity.
During a 5-year-period, four women with an average age of 33 years underwent reconstructive rhinoplasty of their saddle-nose deformity caused by WG, which in every case was in remission regarding the nose at the time of surgery. Restoration of the nasal framework was performed by an L-shaped rib cartilage graft.
The external form and function of the newly reconstructed nose was preserved during an average follow-up period of 42 months for all the patients. No resorption of the rib cartilage graft was observed. A review of the literature found a total of 22 nasal reconstructions for patients affected by WG.
According to this patient series and a review of the literature, external nasal reconstruction for patients affected by WG appears to be safe and effective if the disease is in remission before any operation. Despite concern that high-dose immune suppression therapy may increase the risk of failure in primary nasal dorsal repair, this could not be observed in the patients of this series, all of whom were receiving immunosuppressive medication. Therefore, nasal reconstruction to improve the physical appearance and thus the psychological well-being of these chronically ill patients seems to be justified.

• 出版日期2011-4