Mineralogical changes of bioapatite in femoral bones of mice during pregnancy

作者：Li, Qiao; Lu, Le; Xie, Shengda; Zhang, Penghao; Wang, Shujie; Zhang, Xinyu; Zhou, Zhenlei^*; Li, Zhen^*

来源：Spectroscopy Letters, 2017, 50(6): 336-341.

DOI：10.1080/00387010.2017.1329213

• Bioapatite
• mice
• pregnancy
• Raman spectroscopy
• solubility

Mineralogical changes and solubility of bioapatite in mice cortical bones (2- and 5 months old) were investigated by Raman spectroscopy and inductively coupled plasma spectrometry in this study. The Raman analyses show that the full width at half maximum values of the 960cm(-1) peak exhibit a slight increase during mouse pregnancy, which suggests slightly decreasing crystallinity. Additionally, aging significantly increases the solubility of bone bioapatite. The 1070cm(-1) peak indicates the enriched carbonate incorporation during aging from 2 to 5 months. The elevated solubility of bioapatite and low bone density are consistent with the low crystallinity of bioapatite.

• 出版日期2017
• 单位南京农业大学