A Patient with Tyrosine Kinase 2 Deficiency without Hyper-IgE Syndrome

作者:Kilic Sara S*; Hacimustafaoglu Mustafa; Boisson Dupuis Stephanie; Kreins Alexandra Y; Grant Audrey V; Abel Laurent; Casanova Jean Laurent
来源:Journal of Pediatrics, 2012, 160(6): 1055-1057.
DOI:10.1016/j.jpeds.2012.01.056

摘要

We describe a Turkish patient with tyrosine kinase 2 deficiency who suffered from disseminated Bacille Calmette-Guerin infection, neurobrucellosis, and cutaneous herpes zoster infection. Tyrosine kinase 2 deficiency should be considered in patients susceptible to herpes viruses and intramacrophage pathogens even in the absence of atopy, high serum IgE, and staphylococcal disease. (J Pediatr 2012; 160:1055-7)

  • 出版日期2012-6