Acid-mediated topological control in a functionalized foldamer

作者:Knipe Peter C; Thompson Sam*; Hamilton Andrew D*
来源:Chemical Communications, 2016, 52(39): 6521-6524.
DOI:10.1039/c6cc01496h

摘要

Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.

  • 出版日期2016