Apical Ballooning Syndrome Associated With Isolated Severe Hyponatremia: Case Report and Suggested Pathophysiology

作者：Sagiv Ofer^*; Vukelic Sasa; Czak Steve; Messineo Frank; Coplan Neil L

来源：Reviews in Cardiovascular Medicine, 2012, 13(4): E198-E202.

DOI：10.3909/ricm0647

• Takotsubo cardiomyopathy
• Apical ballooning syndrome
• Broken heart syndrome
• Hyponatremia
• Mechanism

An 82-year-old woman who presented to her primary care physician for preoperative evaluation was incidentally found to have severe hyponatremia (sodium = 118 mmol/L). The patient was then admitted for workup and treatment of hyponatremia. On day 2 of the admission, the patient was found to have new T-wave inversions on a telemetry monitor. Further workup, including an electrocardiogram, cardiac markers, echocardiogram, and a cardiac catheterization were consistent with the diagnosis of apical ballooning syndrome (ABS). Mechanisms of how severe hyponatremia may lead to ABS are discussed as well as a possible approach to the management of severe hyponatremia in postmenopausal women.

• 出版日期2012