Adrenal Castleman disease associated with paraneoplastic pemphigus: a case report and literature review

作者：Dai, Jun; He, Hongchao; Wang, Haofei; Zhu, Yu; Huang, Xin^*; Sun, Fukang^*

来源：International Journal of Clinical and Experimental Medicine, 2017, 10(2): 3840-3844.

• Castleman disease
• adrenal tumor
• paraneoplastic pemphigus
• autoimmune disease
• prognosis

Castleman tumor, a rare lymphoproliferative disorder, is one of the associated tumors in paraneoplastic pemphigus (PNP). Castleman tumor was a frequently reported neoplasm in association with paraneoplastic pemphigus which was caused by an autoimmune reaction originating from the B lymphocytes. Castleman tumor association with PNP is a rarely reported subtype of PNP in China. Early detection and removal of the tumor are crucial for the treatment of tumor- associated autoimmune disease. Here we described a case of a patient with PNP associated Castleman tumor in order to clearly understand and improve the prognosis of the disease. Pathologic evidence proved that it was the follicular dendritic cell sarcoma-like Castleman tumor.

• 出版日期2017
• 单位上海市闵行区中心医院; 上海交通大学