Adverse Reactions to Transfusion of Blood Products and Best Practices for Prevention

作者：Frazier Susan K; Higgins Jacob; Bugajski Andrew; Jones Allison R; Brown Michelle R

来源：Critical Care Nursing Clinics of North America, 2017, 29(3): 271-+.

DOI：10.1016/j.cnc.2017.04.002

• Blood components
• Transfusion
• Adverse transfusion reactions
• TACO
• TRALI
• Restrictive transfusion strategy

Transfusion, a common practice in critical care, is not without complication. Acute adverse reactions to transfusion occur within 24 hours and include acute hemolytic transfusion reaction, febrile nonhemolytic transfusion reaction, allergic and anaphylactic reactions, and transfusion-related acute lung injury, transfusion- related infection or sepsis, and transfusion-associated circulatory overload. Delayed transfusion adverse reactions develop 48 hours or more after transfusion and include erythrocyte and platelet alloimmunization, delayed hemolytic transfusion reactions, post-transfusion purpura, transfusion-related immunomodulation, transfusion-associated graft versus host disease, and, with long-term transfusion, iron overload. Clinical strategies may reduce the likelihood of reactions and improve patient outcomes.

• 出版日期2017-9