The role of chromosomal retention of noncoding RNA in meiosis

作者：Ding Da Qiao; Haraguchi Tokuko; Hiraoka Yasushi^*

来源：Chromosome Research, 2013, 21(6-7): 665-672.

DOI：10.1007/s10577-013-9389-1

• Meiosis
• ncRNA
• meiRNA
• Chromosome pairing
• RNA body

Meiosis is a process of fundamental importance for sexually reproducing eukaryotes. During meiosis, homologous chromosomes pair with each other and undergo homologous recombination, ultimately producing haploid sets of recombined chromosomes that will be inherited by the offspring. Compared with the extensive progress that has been made in understanding the molecular mechanisms underlying recombination, how homologous sequences pair with each other is still poorly understood. The diversity of the underlying mechanisms of pairing present in different organisms further increases the complexity of this problem. Involvement of meiosis-specific noncoding RNA in the pairing of homologous chromosomes has been found in the fission yeast Schizosaccharomyces pombe. Although different organisms may have developed other or additional systems that are involved in chromosome pairing, the findings in S. pombe will provide new insights into understanding the roles of noncoding RNA in meiosis.

• 出版日期2013-12