Miniaturization of a micro-optics array for highly sensitive and parallel detection on an injection moulded lab-on-a-chip

作者:Tran Quang Hung; Sun Yi; Poulsen Carl E**en; Than Linh Quyen; Chin Wai Hoe; Dang Duong Bang; Wolff Anders*
来源:Lab on a Chip, 2015, 15(11): 2445-2451.
DOI:10.1039/c5lc00176e

摘要

A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.

  • 出版日期2015