Pertussis prophylaxis

作者：Shann Frank^*

来源：Australian Prescriber, 2012, 35(6): 176-176.

• antibiotics
• exposure
• whooping cough

Pertussis has significantly increased in Australia, particularly in older children and adults. These patients do not always exhibit classical symptoms and are an important source of infection for young infants.
Antibiotic treatment, isolation of index cases and timely vaccination are important strategies to prevent transmission of pertussis.
Evidence of the efficacy of chemoprophylaxis for pertussis is limited. Assessing efficacy is often confounded by a delay in diagnosis of the index case.
Antibiotic prophylaxis after exposure to pertussis aims to limit transmission to nonimmune contacts. It is recommended for high-risk groups such as unimmunised infants, women in late pregnancy and individuals who may be a source of infection.

• 出版日期2012-12