A transcriptome atlas of rice cell types uncovers cellular, functional and developmental hierarchies

作者：Jiao Yuling; Tausta S Lori; Gandotra Neeru; Sun Ning; Liu Tie; Clay Nicole K; Ceserani Teresa; Chen Meiqin; Ma Ligeng; Holford Matthew; Zhang Hui yong; Zhao Hongyu; Deng Xing Wang; Nelson Timothy^*

来源：Nature Genetics, 2009, 41(2): 258-263.

DOI：10.1038/ng.282

The functions of the plant body rely on interactions among distinct and nonequivalent cell types. The comparison of transcriptomes from different cell types should expose the transcriptional networks that underlie cellular attributes and contributions. Using laser microdissection and microarray profiling, we have produced a cell type transcriptome atlas that includes 40 cell types from rice (Oryza sativa) shoot, root and germinating seed at several developmental stages, providing patterns of cell specificity for individual genes and gene classes. Cell type comparisons uncovered previously unrecognized properties, including cell-specific promoter motifs and coexpressed cognate binding factor candidates, interaction partner candidates and hormone response centers. We inferred developmental regulatory hierarchies of gene expression in specific cell types by comparison of several stages within root, shoot and embryo.

• 出版日期2009-2
• 单位北京大学