A Prospective Study of Weight Training and Risk of Type 2 Diabetes Mellitus in Men

作者：Grontved Anders; Rimm Eric B; Willett Walter C; Andersen Lars B; Hu Frank B^*

来源：Archives of Internal Medicine, 2012, 172(17): 1306-1312.

DOI：10.1001/archinternmed.2012.3138

Background: The role of weight training in the primary prevention of type 2 diabetes mellitus (T2DM) is largely unknown. %26lt;br%26gt;Methods: To examine the association of weight training with risk of T2DM in US men and to assess the influence of combining weight training and aerobic exercise, we performed a prospective cohort study of 32 002 men from the Health Professionals Follow-up Study observed from 1990 to 2008. Weekly time spent on weight training and aerobic exercise (including brisk walking, jogging, running, bicycling, swimming, tennis, squash, and calisthenics/rowing) was obtained from questionnaires at baseline and biennially during follow-up. %26lt;br%26gt;Results: During 508 332 person-years of follow-up (18 years), we documented 2278 new cases of T2DM. In multivariable-adjusted models, we observed a dose-response relationship between an increasing amount of time spent on weight training or aerobic exercise and lower risk of T2DM (P %26lt; .001 for trend). Engaging in weight training or aerobic exercise for at least 150 minutes per week was independently associated with a lower risk of T2DM of 34% (95% CI, 7%-54%) and 52% (95% CI, 45%-58%), respectively. Men who engaged in aerobic exercise and weight training for at least 150 minutes per week had the greatest reduction in T2DM risk (59%; 95% CI, 39%-73%). %26lt;br%26gt;Conclusions: Weight training was associated with a significantly lower risk of T2DM, independent of aerobic exercise. Combined weight training and aerobic exercise conferred a greater benefit.

• 出版日期2012-9-24