Ipsi- and Contralateral Moxibustion Generate Similar Analgesic Effect on Inflammatory Pain

作者：Zuo, Chuan-Yi; Lv, Peng; Zhang, Cheng-Shun; Lei, Ru-Xue; Zhou, Wei; Wu, Qiao-Feng; Luo, Ling; Tang, Yong^*; Yin, Hai-Yan^*; Yu, Shu-Guang^*

来源：Evidence-Based Complementary and Alternative Medicine, 2019, 2019: 1807287.

DOI：10.1155/2019/1807287

• ACUPUNCTURE
• RAT
• BEHAVIOR

The aim of this study was to investigate whether contralateral moxibustion would generate a similar analgesic effect with ipsilateral moxibustion. Contra- and ipsilateral moxibustion were separately applied to Zusanli (ST36) acupoints of inflammatory pain mice. The analgesic effect was evaluated, respectively, by licking/biting time (LBT) of formalin-induced inflammatory pain and thermal withdrawal latency (TWL) of complete Freund's adjuvant- (CFA-) induced inflammatory pain. For formalin-induced pain, compared with formalin group, the total LBT of ipsi- and contralateral moxibustion reduced in both phase I and phase II, but there was no significant difference between ipsi- and contralateral moxibustion. For CFA-induced inflammatory pain, compared with CFA group, TWL of ipsi- and contra-Moxi groups increased immediately after moxibustion intervention; however there was no obvious difference between ipsi- and contralateral moxibustion at any timepoint. It indicated that contralateral moxibustion had a similar analgesic effect with ipsilateral moxibustion in both formalin- and CFA-induced pain. These results suggest that both ipsi- and contralateral moxibustion could be applied for pain relief.

• 出版日期2019
• 单位成都中医药大学