Mitochondrial dysfunction and ovarian aging

作者:Wang Tianren; Zhang Man; Jiang Zongliang; Seli Emre
来源:American Journal of Reproductive Immunology, 2017, 77(5): e12651.
DOI:10.1111/aji.12651

摘要

Mitochondria are double-membrane-bound organelles that are responsible for the generation of most of the cell's energy. Mitochondrial dysfunction has been implicated in cellular senescence in general and ovarian aging in particular. Recent studies exploited this association by studying mitochondrial DNA (mtDNA) copy number as a potential biomarker of embryo viability and the use of mitochondrial nutrients and autologous mitochondrial transfer as a potential treatment for poor ovarian function and response.

  • 出版日期2017-5