Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.

作者：Baltaci Sinem; Kolatan Hatice Efsun; Yilmaz Osman; Kivcak Bijen^*

来源：Turkish Journal of Biology, 2011, 35(6): 757-762.

DOI：10.3906/biy-1006-15

• Anthemis aciphylla
• anti-inflammatory activity
• carrageenin
• paw edema
• cotton pellet

Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.

• 出版日期2011