A new flavonoid from Cudrania cochinchinensis

作者:Chen Li; Zhou Qi; Li Bin; Liu Shi Jun; Dong Jun Xing*
来源:Natural Product Research, 2015, 29(13): 1217-1221.
DOI:10.1080/14786419.2014.997234

摘要

Chemical investigation of the ethanol extract of the roots of Cudrania cochinchinensis led to the isolation of a new flavonoid, (6S,12S,13R)-1-methoxy cyanomaclurin (1), together with seven known compounds, 1,3,5-trihydroxy-4-(3 '-hydroxy-3 '-methylbutyl)xanthone (2), 1,3,6-trihydroxy-4-prenylxanthone (3), 1,3,6,7-tetrahydroxyxanthone (4), 1,3,5,6-tetrahydroxyxanthone (5), 1,3,6-trihydroxy-5-methoxyxanthone (6), resveratrol (7) and oxyresveratrol (8). The structure of compound 1 was elucidated on the basis of 1D and 2D NMR spectra and the HR-ESI-MS data. The absolute stereochemistry was deduced via Rh-2(OCOCF3)(4)-induced CD and NOESY spectra.