Addicted to Myc-but why?

作者:von Eyss Bjoern; Eilers Martin*
来源:Genes & Development, 2011, 25(9): 895-897.
DOI:10.1101/gad.2053311

摘要

Many tumors continuously depend on the initiating oncogenes, but whether this extends to their downstream targets is unclear. In this issue of Genes & Development, Sodir and colleagues (pp. 907-916) demonstrate an essential role for endogenous Myc proteins in maintaining the tumor microenvironment, providing an unexpected molecular explanation for addiction to Myc.

  • 出版日期2011-5-1