Four new cycloartane glycosides from Thalictrum fortunei

作者：Zhang, XT; Zhang, LH; Ye, WC^*; Zhang, XL; Yin, ZQ; Zhao, SX; Yao, XS

来源：Chemical & Pharmaceutical Bulletin, 2006, 54(1): 107-110.

DOI：10.1248/cpb.54.107

• Thalictrum fortunei
• Ranunculaceae
• cycloartane glycoside

Four new cycloartane glycosides were isolated from the aerial parts of Thalictrum fortunei (Ranunculaceae). The chemical structures of these new glycosides were elucidated as 3-O-beta-o-glucopyranosyl-(1 -> 4)-beta-D-fucopyranosyl (22S,24Z)-cycloart-24-en-3 beta,22,26-triol 26-O-beta-D-glucopyranoside, 3-O-beta-D-glucopyranosyl-(1 -> 4)-beta-D-fucopyranosyl (22S,24Z)-cycloart-24-en-3 beta,22,26-triol 26-O-beta-D-quinovopyranosyl-(1 -> 6)-beta-D-glucopyranoside, 3-O-beta-D-glucopyranosyl-(1 -> 4)-beta-D-fucopyranosyl (22S,24Z)-cycloart-24-en-beta,22,26-triol 26-O-beta-D-xylopyranosyl(1 -> 6)-beta-D-glucopyranoside, and 3-O-beta-o-glucopyranosyl-(1 -> 4)-beta-D-fucopyranosyl (22S,24Z)-cycloart-24-en-3 beta,22,26-triol 26-O-alpha-L-arabinopyranosyl-(1 -> 6)-beta-D-glucopyranoside by extensive NMR methods, HR-ESI-MS, and hydrolysis. This is the first report of (22S,24Z)-3 beta,22,26-trihydroxycycloartan-24-ene (thelictogenin A, 5) 14 being glycosylated at C-26.

• 出版日期2006-1
• 单位中国药科大学; 江苏大学; 暨南大学