科研之友
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摘要
Background: Volar plating is commonly used in the management of distal radius fractures; bioresorbable plates have attractive features. We compared a bioresorbable plate with a latest generation and an established locked titanium plate. Methods: Twenty-four fresh-frozen radii (12 pairs) were assigned to three mean bone mineral density-matched groups of eight radii each. A standardized extraarticular distal radius fracture was created and plated using one implant type per group. Postplating stiffness and displacement were studied in a first axial-loading test (15 cycles at 250 N). Next, biodegradation was simulated by 4 weeks' immersion in phosphate-buffered saline, followed by a second axial test. Finally, the specimens underwent cyclic loading (2,400 cycles at 250 N). Results: It is clear from the initial test that the LCP plate was significantly stiffer and displaced less than the bioresorbable plate. The outcome of the postimmersion tests is that one bioresorbable plate failed early on after 4 weeks' immersion, and the remaining bioresorbable plates and the T plates did not differ significantly. Cyclic tests conclude that the LCP plate was significantly superior to the other systems. One T plate and four of the bioresorbable plates failed, but none of the LCP plates failed. In the bioresorbable constructs, stability, time to failure, and bone mineral density were significantly correlated. Conclusions: The LCP plate was biomechanically superior and may be generally recommended for the volar plating of distal radius fractures. Except one plate failure, the bioresorbable plate was similar to the T plate in the quasi-static tests and should, therefore, be considered for clinical studies, with patient selection confined, initially, only to candidates with good bone stock quality.
- 出版日期2010-4
