Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility

作者：Boynukalin Fazilet Kubra; Esinler Ibrahim^*; Guven Suleyman; Gunalp Serdar

来源：Archives of Gynecology and Obstetrics, 2012, 286(6): 1577-1580.

DOI：10.1007/s00404-012-2476-2

• Hyaluronan binding assay
• Sperm quality
• Intrauterine insemination (IUI)
• ART

Purpose To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles. %26lt;br%26gt;Methods This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who suffered from unexplained infertility and underwent controlled ovarian hyperstimulation (COH) and IUI were enrolled into the study. %26lt;br%26gt;Results From the 71 IUI patients, the clinical pregnancy rate was 14.1 % (10 of 71). HB ratio from the overall patient number was 48.6 +/- 25.9. The mean HB ratio in pregnant and non-pregnant groups was comparable (50.2 +/- 25.2 vs. 48.3 +/- 26.2, respectively, p %26gt; 0.05). %26lt;br%26gt;Conclusions Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility.

• 出版日期2012-12