A Concise Access to 3-Substituted 2-Pyrones

作者:Frebault Frederic; Oliveira Maria Teresa; Wostefeld Eckhard; Maulide Nuno*
来源:Journal of Organic Chemistry, 2010, 75(22): 7962-7965.
DOI:10.1021/jo101843a

摘要

The development of a modular synthesis of 3-substituted-2-pyrones is described The attainment of this strategy hinges on a new electrophilic pyrone derivative which can be readily prepared on a multigram scale and which performs very competently in metal-catalyzed cross-coupling reactions with a variety of nucleophiles

  • 出版日期2010-11-19