Age-Disparate Partnerships and Risk of HIV-1 Acquisition Among South African Women Participating in the VOICE Trial

作者：Balkus Jennifer E^*; Nair Gonasagrie; Montgomery Elizabeth T; Mishra Anu; Palanee Phillips Thesla; Ramjee Gita; Panchia Ravindre; Selepe Pearl; Richardson Barbra A; Chirenje Zvavahera M; Marrazzo Jeanne M

来源：JAIDS: Journal of Acquired Immune Deficiency Syndromes , 2015, 70(2): 212-217.

DOI：10.1097/QAI.0000000000000715

• HIV-1 in women
• age-disparate relationships
• male partner
• South Africa
• sexual behavior

A recent analysis from South Africa reported no association between age-disparate relationships and HIV-1 acquisition. We assessed the association between male partner age and HIV-1 acquisition among South African women participating in the VOICE trial. Of 4077 women enrolled, 3789 had complete data; 26% and 5% reported having a partner >5 and >10 years older at enrollment, respectively. Reporting a partner >5 years older (hazard ratio = 1.00; 95% confidence interval: 0.74 to 1.35) or >10 older (hazard ratio = 0.92; 95% confidence interval: 0.49 to 1.74) was not associated with HIV-1 acquisition. These data corroborate recent reports and may suggest a shift in local epidemiology of heterosexual HIV-1 transmission.

• 出版日期2015-10-1