A new sesquiterpene from the Hainan gorgonian Menella kanisa Grassoff

作者:Chen Min; Han Lei; Wang Yu; Zhang Xiu Li; Wang Chang Yun*
来源:Natural Product Research, 2014, 28(15): 1147-1151.
DOI:10.1080/14786419.2014.918122

摘要

Chemical investigation of the gorgonian Menella kanisa Grassoff collected from the South China Sea led to the isolation of a new sesquiterpene, menecubebane A (1), together with three known compounds, 8-methoxy-trans-calamenene (2), 8,9-dihydro-linderazulene (3) and (3)-oleanan-3-ol (4). The structure of 1 was determined by detailed analysis of the spectroscopic data especially the NOESY spectrum. All the compounds were evaluated for their cytotoxic, brine shrimp lethal and antifouling activities.