An efficient strategy for formation of C-N bond by benzyl chloride over nano alpha-Fe2O3

作者：Tang, Huihui; Wang, Hongxia; Lu, Bin^*; Zhao, Jingxiang; Cai, Qinghai^*

来源：Molecular Catalysis, 2017, 431: 27-31.

DOI：10.1016/j.mcat.2017.01.024

• Secondary amines
• C-N bonding formation
• alpha-Fe2O3
• N-benzylation

Nano alpha-Fe2O3 was prepared using PEG-400 as dispersant by a simple sol-gel method, as proved by XRD, SEM, TEM and ICP-MS. The alpha-Fe2O3 was demonstrated to be an efficient catalyst for N-benzylation of aliphatic and aromatic amines with benzyl chloride and benzyl bromide in 8% Na2CO3 aqueous solution, achieving ca. 100% conversions and > 82% selectivity to monosubstituted products for aromatic amines and higher selectivity to disubstituted products for aliphatic amines at 50-80 degrees C and reaction time 1-3 h. The catalyst was easily recovered and reused effectively three runs without a significant loss of catalytic activity.

• 出版日期2017-4
• 单位哈尔滨师范大学