An Electrochemical Study on Chlorhexidine Gluconate Addition to Normal Saline for Oral Implant Applications

作者：Bhola Shaily M^*; Kundu Sukumar; Alabbas Faisal; Mishra Brajendra; Olson David L

来源：International Journal of Electrochemical Science, 2013, 8(4): 5172-5182.

• chlorhexidine gluconate
• corrosion
• dental implant
• titanium alloy

Chlorhexidine gluconate (CHG) is an effective bactericidal agent commonly used in periodontics and oral and maxillofacial procedures. Upon the application of CHG in these procedures, an implant or prosthesis can come in contact with CHG which might alter the electrochemistry at the metal-body fluid interface. The effect of 0.01% CHG addition to normal saline (NS) on the corrosion behavior of Ti1 implant alloy has been investigated using various electrochemical techniques to simulate the use of CHG in the oral environment. Electrochemical testing was performed at 298 K under naturally aerated conditions using techniques such as open circuit potential (OCP), electrochemical impedance spectroscopy (EIS), potentiodynamic and potentiostatic measurements. On addition of CHG to normal saline, the corrosion rate of Ti1 alloy increases, more so with increasing exposure time. EIS analysis reveals the presence of two time constants in the presence of CHG in contrast to a one time constant in pure normal saline. It is recommended to use CHG in the presence of a corrosion inhibitor for its safe use in various oral procedures on patients with titanium implants/prostheses.

• 出版日期2013-4