Distribution of Phage-Associated Virulence Genes in Pharyngeal Group A Streptococcal Strains Isolated in Italy

作者:Vitali Luca Agostino*; D'Ercole Stefania; Petrelli Dezemona; Di Luca Maria Chiara; Rombini Silvia; Prenna Manuela; Ripa Sandro
来源:Journal of Clinical Microbiology, 2009, 47(5): 1575-1577.
DOI:10.1128/JCM.00925-08

摘要

The presence and assortment of 16 known virulence/resistance genetic determinants carried by prophages or prophage-like elements were tested in 212 clinical group A Streptococcus (GAS) strains and related to available data from SmaI macrorestriction/pulsed-field gel electrophoresis analysis and emm typing. A strong correlation existed among the three analyses. This finding supports the substantial contribution to the evolution and diversification of the GAS genome attributed to phages.

  • 出版日期2009-5