摘要
The stereomers of hept-6-ene-2,5-diol derivatives were conceived as useful chiral intermediates and were synthesized starting from sulcatol using two lipase-catalyzed acylation reactions as the key steps. The versatility of the intermediates was demonstrated by converting OH them to the titled tetrahydropyran, macrolide, and macrodiolide compounds using standard synthetic protocols.
- 出版日期2014-9-5