ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data

作者:Bystry Vojtech; Reigl Tomas; Krejci Adam; Demko Martin; Hanakova Barbora; Grioni Andrea; Knecht Henrik; Schlitt Max; Dreger Peter; Sellner Leopold; Herrmann Dietrich; Pingeon Marine; Boudjoghra Myriam; Rijntjes Jos; Pott Christiane; Langerak Anton W; Groenen Patricia J T A; Davi Frederic; Brueggemann Monika; Darzentas Nikos*
来源:Bioinformatics, 2017, 33(3): 435-437.
DOI:10.1093/bioinformatics/btw634

摘要

Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations.

  • 出版日期2017-2-1