Amotsaokonal A-C, benzaldehyde and cycloterpenal from Amomum tsao-ko

作者：Hong Seong Su; Lee Ji Hye; Choi Yun Hyeok; Jeong Wonsik; Ahn Eun Kyung; Lym Seung Ho; Oh Joa Sub^*

来源：Tetrahedron Letters, 2015, 56(48): 6681-6684.

DOI：10.1016/j.tetlet.2015.10.045

• Amomum tsao-ko
• Amotsaokonal
• Benzaldehyde
• Cycloterpenal

One new benzaldehyde (I) and two new cycloterpenals (2 and 3) along with five known compounds (4-8) have been isolated from the fruits of Amomum tsao-ko. Their structures were elucidated by a combination of 1D and 2D NMR, and HRESI-MS spectrometry. All isolates were tested for their inhibitory activities on LPS-induced nitric oxide production in RAW264.7 cells. Among the isolates, compounds 2 and 4 found to inhibit nitric oxide production with the IC50 values of 94.8 and 61.2 mu M.

• 出版日期2015-12-2