Lu-177-PSMA Radioligand Therapy for Prostate Cancer

作者:Fendler Wolfgang P*; Rahbar Kambiz; Herrmann Ken; Kratochwil Clemens; Eiber Matthias
来源:Journal of Nuclear Medicine, 2017, 58(8): 1196-1200.
DOI:10.2967/jnumed.117.191023

摘要

Lu-177-prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) using inhibitors of PSMA is a novel therapeutic option in patients withmetastatic castration-resistant prostate cancer. The current literature suggests that this therapy is well tolerated and effective. On the basis of clinical need and current evidence, the therapy is being implemented in a growing number of centers worldwide. Here, we review important aspects of Lu-177-PSMA RLT, including patient stratification, the therapy protocol, concomitant medication, and follow-up, to inform medical staff involved in the RLT and care of patients with metastatic castration-resistant prostate cancer.

  • 出版日期2017-8-1