Protean Manifestations of Vitamin D Deficiency, Part 3: Association with Cardiovascular Disease and Disorders of the Central and Peripheral Nervous Systems

作者：Bell David S H

来源：Southern Medical Journal, 2011, 104(5): 340-344.

DOI：10.1097/01.SMJ.0000397894.02150.5f

Vitamin D deficiency is associated with the risk factors of inflammation, insulin resistance and endothelial dysfunction, and left ventricular hypertrophy. As a result there is an increase in cardiovascular events (CVEs) associated with vitamin D deficiency. Vitamin D deficiency itself or secondary hyperparathyroidism or both may be responsible for the increase in CVEs. Correction of vitamin D deficiency may decrease the incidence of CVEs. Vitamin D deficiency is also associated with Alzheimer disease, schizophrenia, depression, and chronic pain and muscle weakness. Vitamin D deficiency is early treated with oral vitamin D supplements which may improve the manifestations of the diseases associated with vitamin D deficiency.

• 出版日期2011-5