Analytical characterization and antimicrobial properties of novel copper nanoparticle-loaded electrosynthesized hydrogel coatings

作者：Cometa Stefania; Iatta Roberta; Ricci Maria Antonietta; Ferretti Concetta; De Giglio Elvira^*

来源：Journal of Bioactive and Compatible Polymers, 2013, 28(5): 508-522.

DOI：10.1177/0883911513498960

• copper nanoparticles
• antimicrobial surfaces
• Infection prevention
• electrochemical polymerization
• hydrogel

In this study, a novel antimicrobial coating was developed to avoid infections and to provide sterile conditions for stainless steel devices. Poly(ethylene glycol diacrylate) hydrogel thin films were modified with copper-based nanoparticles, following two different entrapment procedures. These coatings were firmly attached on metal substrates by means of a simple and fast electrochemical polymerization technique. The surface composition of the Cu nanoparticles-modified hydrogel coatings and their bactericidal effect against Staphylococcus aureus and Escherichia coli was studied, and the efficacy of such systems in preventing bacterial infections demonstrated.

• 出版日期2013-9