A new biomimetic route to engineer enzymatically active mechano-responsive materials

作者:Rios Cesar; Longo Johan; Zahouani Sarah; Garnier Tony; Vogt Cedric; Reisch Andreas; Senger Bernard; Boulmedais Fouzia; Hemmerle Joseph; Benmlih Karim; Frisch Benoit; Schaaf Pierre; Jierry Loic; Lavalle Philippe
来源:Chemical communications, 2015, 51(26): 5622-5625.
DOI:10.1039/c5cc00329f

摘要

Using modified beta-galactosidase covalently linked to cross-linked polyelectrolyte multilayers (PEM), catalytically active materials have been designed. Their enzymatic activity can be modulated, partially in a reversible way, simply by stretching. This strategy, based on enzyme conformational changes, constitutes a new tool for the development of biocatalytic mechano-responsive materials.

  • 出版日期2015