Anterior and anterolateral approach in the treatment of thoracic and lumbar vertebral metastasis causing spinal cord compression

作者：Vargas Lopez Antonio Jose; Fernandez Carballal Carlos; Panadero Useros Teresa; Aracil Gonzalez Cristina; Garbizu Vidorreta Jose Manuel; Gonzalez Rodrigalvarez Rosario

来源：Neurocirugia, 2015, 26(3): 126-136.

DOI：10.1016/j.neucir.2014.11.003

• Spine
• Metastasis
• Treatment
• Surgery
• Anterior approach

Objectives: To analyse the results of the anterior and anterolateral approaches in the treatment of thoracic and lumbar spine metastasis.
Materials and methods: Patients who underwent surgery between 2003 and 2012 in our institution using an anterior or an anterolateral approach for the treatment of thoracic or lumbar spine metastasis were retrospectively reviewed.
Results: Twenty-two patients with median age of 49.5 years (26-73 years) and median follow-up of 9.5 months (0-96 months) were analysed. The most common primary malignancies were renal cell carcinomas and breast adenocarcinomas. Before the intervention, 12 (54.5%) patients were able to walk (Frankel D and E). Preoperative arteriography was performed in 14(63.6%) patients, and 7 (31.8%) of them underwent tumour embolisation. Medical complications occurred in 5 (22.7%) patients during the immediate postoperative period, 2 (9.1%) of whom died. At the end of follow-up, 16 (72%) of the remaining 20 patients were able to walk (Frankel D and E). Ninety percent of the patients could reduce at least 50% of their analgesic drug requirements. During follow-up 16 patients died, with a median survival of 10 months (range 0-48 months).
Conclusions: Resection of thoracolumbar vertebral metastases by an anterior/anterolateral approach, despite its considerable risk of morbidity and mortality, offers the possibility of significant improvement in the quality of life of the patient; and it does so not only by preserving or restoring their ability to walk but also by ameliorating pain. Preoperative angiography, considering the embolisation of the lesion, is an important tool.

• 出版日期2015-6