Direct oxidative amidation between methylarenes and amines in water

作者：Wang, Tao^*; Yuan, Lin; Zhao, Zhenguang; Shao, Ailong; Gao, Meng; Huang, Yangfei; Xiong, Fei; Zhang, Huali; Zhao, Junfeng

来源：Green Chemistry, 2015, 17(5): 2741-2744.

DOI：10.1039/c5gc00299k

• C-H ACTIVATION
• PRIMARY ALCOHOLS
• AMIDE SYNTHESIS
• BOND FORMATION
• ALDEHYDES
• ESTERIFICATION
• CATALYSIS
• AROYLATION
• PEPTIDES
• LIGATION

An environmentally friendly direct oxidative amidation between methylarenes and free amines was developed. The aromatic amide could be prepared efficiently from raw chemicals by employing TBHP as a "green" oxidant with co-catalysis of TBAI and FeCl3 in water.

• 出版日期2015
• 单位江西师范大学