科研之友
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摘要
A practical and efficient protocol has been developed for the synthesis of 2-imino-4-thiazolidinone through a unique one pot three-component reaction of variety of amines, isothiocyanate and ethylbromoacetate in water. The method is free of catalyst and other toxic solvents, has shorter reaction times, high-yielding, effortlessness in isolation of product, making it more eco-friendly process, and suitable for large scale operation.
- 出版日期2014-9
