Using Mice to Treat (Wo)men: Mining Genetic Changes in Patient Xenografts to Attack Breast Cancer

作者:Oesterreich Steffi*; Brufsky Adam M; Davidson Nancy E
来源:Cell Reports, 2013, 4(6): 1061-1062.
DOI:10.1016/j.celrep.2013.09.008

摘要

In this issue of Cell Reports, Li et al. show that the analysis of genetic changes in patient-derived xenografts can reveal crucial details of tumor evolution, such as the emergence of functional estrogen receptor mutations in endocrine-resistant breast cancer.

  • 出版日期2013-9

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