Amine-promoted, organocatalytic aziridination of enones

作者：Armstrong Alan^*; Baxter Carl A; Lamont Scott G; Pape Andrew R; Wincewicz Richard

来源：Organic Letters, 2007, 9(2): 351-353.

DOI：10.1021/ol062852v

A novel method is presented using N-N ylides (prepared by in situ amination of a tertiary amine) for the aziridination of a range of enone systems. The amine may be used sub-stoichiometrically, and promising levels of enantioselectivity are observed with quinine as promoter.

• 出版日期2007-1-18