科研之友
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摘要
A dianionic Ireland-Claisen rearrangement of chiral, nonracemic alpha-methyl-beta-hydroxy allylic esters has been developed that proceeds with high diastereoselectivity and provides products containing three contiguous stereogenic carbons, including a quaternary center. The potential utility of the rearrangement for complex molecule synthesis is also demonstrated.
- 出版日期2014-5-2
