A Simple Neobladder Using a Porcine Model: The Double Limb U-Pouch

作者：Werntz Ryan P; Shoureshi Poone; Gillis Kyle; Kapadia Akash; Jiang David; Amling Christopher; Barry John M

来源：Urology, 2018, 114: 198-201.

DOI：10.1016/j.urology.2017.11.031

OBJECTIVE To create a simple neobladder and determine whether the double-limb U-Pouch (D-LUP) has the same capacity and compliance as a Studer or Camey I neobladder. To develop an orthotopic diversion that can be applied to robotic surgery with laboratory data supporting the concept.
MATERIALS AND METHODS Kidneys, ureters, bladders, and small intestine were obtained from pigs at the time of scheduled autopsy after completion of institutionally approved investigational trauma protocols. A Camey I neobladder, spherical neobladder, and D-LUP, were constructed from 40-cm segments of small intestine. They were compared for capacity, compliance, and pouch-to-urethra anastomotic distance.
RESULTS The cystometric capacity at 30 cm H2O for the Camey I, Studer, and D-LUP neobladders were 250 mL, 350 mL, and 430 mL, respectively. The pouch-to-urethra anastomotic distance was 0 cm for the Camey I, 10 cm for the spherical reservoir, and 0 cm for the D-LUP. Compliance was 10 mL/cm H2O for the Camey 1, 15 mL/cm H20 for the sphere, and 16 mL/cm H20 for the D-LUP.
CONCLUSION The D-LUP neobladder was simple to construct, had a more dependent ileo-urethrostomy site, larger capacity, and similar compliance when compared with a spherical neobladder. Published by Elsevier Inc.

• 出版日期2018-4