Analysis of a 26 kb region on the left arm of yeast chromosome XV

作者：Mannhaupt G; Vetter I; Schwarzlose C; Mitzel S; Feldmann H

来源：Yeast, 1996, 12(1): 67-76.

DOI：10.1002/(SICI)1097-0061(199601)12:1<67::AID-YEA884>3.0.CO;2-F

• Saccharomyces cerevisiae
• chromosome XV
• ORFs
• predictable functions
• regulatory elements

In the framework of the EC programme for sequencing yeast chromosome XV, we have determined the nucleotide sequence of a 26 kb region. Subsequent analysis revealed 13 non-overlapping open reading frames, three of which correspond to known yeast genes. A pair of tRNA genes associated with remnant Ty elements were localized in this region. From structural parameters and/or similarity searches with entries in the current data libraries, a preliminary functional assessment of several of the putative novel gene products can be made. The gene density in this region amounts to one gene in 2 kb. Protein coding regions occupy 61% of the total DNA sequence. Within the intergenic regions, potential regulatory elements can be predicted. The data obtained here may serve as a basis for a more detailed biochemical analysis of the novel genes. The complete nucleotide sequence of the 26 kb segment as depicted in Figure 1 has been deposited at the EBI data library under Accession Number X91067.

• 出版日期1996-1