Antimony(III) chloride impregnated on alumina - An efficient and economical Lewis acid catalyst for one-pot synthesis of dihydropyrimidinones under solvent-free conditions

作者：Kapoor KK^*; Ganai BA; Kumar S; Andotra CS

来源：Canadian Journal of Chemistry, 2006, 84(3): 433-437.

DOI：10.1139/V06-019

• Biginelli dihydropyrimidinones synthesis
• SbCl3-Al2O3
• MW
• sonication
• solid supported

The antimony(III) chloride impregnated on alumina efficiently catalyses a one-pot, three-component condensation reaction among an aldehyde, a beta-ketoester, and urea or thiourea to afford the corresponding dihydropyri midin ones in good to excellent yields. The reactions are probed in microwave (MW), ultrasonic, and thermal conditions and the best results are found using MW under solvent-free conditions.

• 出版日期2006-3