Aminoquinoline based highly sensitive fluorescent sensor for lead(II) and aluminum(III) and its application in live cell imaging

作者：Anand Thangaraj; Sivaraman Gandhi; Mahesh Ayyavu^*; Chellappa Duraisamy

来源：Analytica Chimica Acta, 2015, 853: 596-601.

DOI：10.1016/j.aca.2014.11.011

• Anthracene
• Lead(II)
• Live cell imaging
• Turn-on
• Time dependent-density functional theory

We have synthesized a new probe 5-((anthracen-9-ylmethylene) amino)quinolin-10-ol (ANQ) based on anthracene platform. The probe was tested for its sensing behavior toward heavy metal ions Hg2+, Pb2+, light metal Al3+ ion, alkali, alkaline earth, and transition metal ions by UV-visible and fluorescent techniques in ACN/H2O mixture buffered with HEPES (pH 7.4). It shows high selectivity toward sensing Pb2+/Al3+ metal ions. Importantly, 10-fold and 5-fold fluorescence enhancement at 429 nm was observed for probe upon complexation with Pb2+ and Al3+ ions, respectively. This fluorescence enhancement is attributable to the prevention of photoinduced electron transfer. The photonic studies indicate that the probe can be adopted as a sensitive fluorescent chemosensor for Pb2+ and Al3+ ions.

• 出版日期2015-1-1