A composite monolithic column fabricated with functionalized nanodiamond and its application in separation of small molecules

作者：Wei, Aile; Dong, Peipei; Cui, Beijiao; Wang, Fengqing; Liu, Haiyan^*; Bai, Ligai; Yan, Hongyuan

来源：Journal of Porous Materials, 2017, 24(2): 373-380.

DOI：10.1007/s10934-016-0270-4

• Nanodiamond
• Composite
• Polymer monolithic column
• Separation of small molecules
• High performance liquid

A nanodiamond-based composite monolithic column was fabricated by redox initiation for high performance liquid chromatography (HPLC). The functionalized nanodiamond was modified via Fenton Reagent and 3-methacryl oxypropyltrimethoxysilane (KH-570). After being optimized conditions, composite monolithic columns were prepared with functionalized ND (f-ND) as functional monomer, dipentaerythritol hexaacrylate and ethylene dimethacrylate as crosslinking agents, dodecanol and 1-propanol as co-porogens, dibenzoyl peroxide and N,N-dimethyl aniline as initiators. Characterizations of the resulting nanocomposite, including fourier transform infrared spectra, scanning electron microscopy images, thermal gravimetric analysis, mercury intrusion porosimetry and nitrogen adsorption-desorption isotherm were all carried out in detail. Bigger specific surface area, better mechanical stability, thermostability property and orderliness skeleton structure with flow-through channels and macroporous of the composite monolithic column was exhibited than those columns without f-ND added. At last, the nanodiamond-based composite monolithic column was used to separate a series of small molecules including acidic, alkaline and neutral compounds with good resolution and reproducibility in HPLC.

• 出版日期2017-4
• 单位河北大学