A Minimally Invasive Microdevice for Molecular Sampling and Analysis

作者:Cosnier Marie Line*; Martin Franck; Bouamrani Ali; Berger Francois; Caillat Patrice
来源:IEEE Transactions on Biomedical Engineering, 2009, 56(12): 2898-2904.
DOI:10.1109/TBME.2009.2026582

摘要

In this paper, we present a new minimally invasive biopsy microdevice adapted to proteomic mass spectrometry analysis. The concept is born from a multidisciplinary collaboration in fields of proteomics, cancer research, and microtechnology. In mixing different skills, we have developed and manufactured a miniaturized biopsy device using microtechnology techniques in order to minimize tissue damage during surgical gesture. Dedicated chemically functionalized areas were added to the device in order to increase capture yield and specificity during tissue contact. Fields of application range from cancer research to the study of neurodegenerative diseases.

  • 出版日期2009-12
  • 单位中国地震局

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