Italian multicenter experience with flow-diverter devices for intracranial unruptured aneurysm treatment with periprocedural complications-a retrospective data analysis

作者：Briganti Francesco^*; Napoli Manuela; Tortora Fabio; Solari Domenico; Bergui Mauro; Boccardi Edoardo; Cagliari Enrico; Castellan Lucio; Causin Francesco; Ciceri Elisa; Cirillo Luigi; De Blasi Roberto; Delehaye Luigi; Di Paola Francesco; Fontana Andrea; Gasparotti Roberto; Guidetti Giulio; Divenuto Ignazio; Iannucci Giuseppe; Isalberti Maurizio; Leonardi Marco; Lupo Fernando; Mangiafico Salvatore; Manto Andrea; Menozzi Roberto; Muto Mario; Nuzzi Nunzio Paolo

来源：Neuroradiology, 2012, 54(10): 1145-1152.

DOI：10.1007/s00234-012-1047-3

• Flow diverter device
• Pipeline embolization device
• Silk embolization device
• Intracranial aneurysms
• Endovascular treatment

We report the experiences of 25 Italian centers, analyzing intra- and periprocedural complications of endovascular treatment of intracranial aneurysms using Silk (Balt Extrusion, Montmorency, France) and pipeline embolization devices (EV3 Inc, Irvine California). %26lt;br%26gt;Two hundred seventy-three patients with 295 cerebral aneurysms, enrolled in 25 centers in Italy and treated with the new flow-diverter devices, were evaluated; 142 patients were treated with Silk and 130 with pipeline (in one case, both devices were used). In 14 (5.2 %) cases devices were used with coils. Aneurysm size was %26gt; 15 mm in 46.9 %, 5-15 mm in 42.2 %, and %26lt; 5 mm in 10.8 %. Aneurysm locations were supraclinoid internal carotid artery (ICA) in 163 cases (55.2 %), cavernous ICA in 76 (25.7 %), middle cerebral artery in 11 (3.7 %), PCoA in 6 (2 %), and ACoA in 2 (0.7 %); the vertebrobasilar system accounted for 32 cases (10.8 %) and PCA in 5 (1.7 %). %26lt;br%26gt;Technical adverse events occurred with 59 patients (21.6 %); 5 patients died after ischemic events, 10 to hemorrhagic complications, and 1 from external ventricular drain positioning. At 1 month, morbidity and mortality rates were 3.7 % and 5.9 %, respectively %26lt;br%26gt;Our retrospective study confirms that morbidity and mortality rates in treatment with FDD of unruptured wide-neck or untreatable cerebral aneurysms do not differ from those reported in the largest series.

• 出版日期2012-10