A Sustainable and Efficient Synthesis of Benzyl Phosphonates Using PEG/KI Catalytic System

作者：Disale Shamrao; Kale Sandip; Abraham George; Kahandal Sandeep; Sawarkar Ashish N; Gawande Manoj B^*

来源：Frontiers in Chemistry, 2016, 4: UNSP 35.

DOI：10.3389/fchem.2016.00035

• sustainability
• KI +K2CO3
• PEG
• synthesis of benzyl phosphonates
• green chemistry

An efficient and expedient protocol for the synthesis of benzyl phosphonates using KI/K2CO3 as a catalytic system and PEG-400 as benign solvent has been developed. The reaction proceeds smoothly at room temperature achieving excellent selectivity and yield of the corresponding products. The combination of PEG-400, KI, and K2CO3 in this reaction avoids the need of volatile/toxic organic solvents and reactive alkali metals or metal nanoparticles/hydrides. We believe that this benign combination (PEG-400 and KI) could be used for other related organic transformations.

• 出版日期2016-8-16