Dip-Pen Nanolithography of Bioactive Peptides on Collagen-Terminated Retinal Membrane

作者:Sistiabudi Rizaldi; Ivanisevic Albena*
来源:Advanced Materials, 2008, 20(19): 3678-+.
DOI:10.1002/adma.200800950

摘要

Dip-pen nanolithography is used to directly modify freshly dissected eye tissues with biologically active collagen-binding peptide molecules. The results address the challenge of surface heterogeneity and utilize dip-pen nanolithography to control the localization and concentration of molecules on a collagen-terminated tissue-derived surface. This method can allow the development of scaffolds for treatment of age-related macular degeneration.

  • 出版日期2008-10-2