科研之友
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摘要
Chitosan is a biodegradable and biocompatible polymer with unique properties derived from marine resources, it is expected as important raw material for nanofibers with wide range of applications. Chitosan and its composite nanofibers have been fabricated by traditional spinning processes such like wet spinning or electrospinning, but these processes are complex, using harmful solvent or high voltage with lower safety. In search of more simple and safe nanofiber fabrication method applicable to chitosan, six kinds of novel nanofiber fabrication methods are reviewed, these methods are divided into two major categories of "small similar to large" approach and "large similar to small" approach. "Small similar to large" approach includes variety of spinning processes ( such as rotary jet-spinning, handspinning and solution blowing) and two freeze casting processes (simple freeze-drying and jet-rapid freezing), while star burst system as an example of "large similar to small" approach. Both advantages and disadvantages of each method are compared from the viewpoint of fiber diameter, fiber orientation and the applicability to chitosan. A new innovative idea of combining ultrasonic atomization and freeze casting process for chitosan nanofibers is also provided in this review. Ultrasonic atomization combined with freeze casting method is simple and avoids usage of volatile solvents. Chitosan nanofibers obtained by this innovative method could be applicable to biomedical engineering and food engineering due to both chitosan's characteristics and the safety of fabrication process.
- 出版日期2014-11
- 单位扬州大学
