Application of nanostructured drug delivery systems in immunotherapy of cancer: a review

作者:Asadi Nahideh; Davaran Soodabeh; Panahi Yunes; Hasanzadeh Arash; Malakootikhah Javad; Moafi Hadi Fallah; Akbarzadeh Abolfazl*
来源:Artificial Cells Nanomedicine and Biotechnology, 2017, 45(1): 18-23.
DOI:10.1080/21691401.2016.1178136

摘要

The cancer immunotherapy method uses the specificity of the immune system to provide a more effective than more conventional treatments, such as chemotherapy and radiotherapy. Immunotherapy has two main strategies (passive or active) to organize the immune system. Passive strategies use advantage of tumor-hyperpermeable cells, which have enhanced permeability and retention effects. Nanoparticles due to their better accumulation within tissues and cells of the immune system are well suitable for delivery of immune therapies such as vaccines or adjuvants. In this review, we explained application of nanotechnology in immunotherapy of cancer.

  • 出版日期2017-2